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53rd NARECOM - When Engineering Meets Biology: Capturing Real-World Exposure to Airborne Particles and Gases
You are invited to our NARECOM seminar on March 4th, 2026, at 2:30 p.m. The presentation given by Dr. Tereza Červená from the Institute of Experimental Medicine of the CAS will introduce a mobile air–liquid interface (ALI) portable exposure system (PETS) designed to capture variable exposure scenarios under controlled laboratory and real-world conditions. Join Zoom Meeting https://cesnet.zoom.us/j/95638405007
Abstract:
When Engineering Meets Biology: Capturing Real-World Exposure to Airborne Particles and Gases
Mgr. Tereza Červená, PhD.
Institute of Experimental Medicine AS CR, v.v.i.
Air pollution and engineered aerosols represent highly variable exposure scenarios, with particle size, number concentration, and chemical composition strongly dependent on source and generation conditions. This presentation introduces a mobile air–liquid interface (ALI) portable exposure system (PETS) designed to capture this variability under controlled laboratory and real-world conditions. The platform enables direct exposure of human airway epithelial models to complete aerosols, preserving gas–particle interactions and realistic deposition of ultrafine and nanoscale particles. Exposure sources include traffic-related engine emissions, ambient urban air, and nanoparticles generated by spark ablation using different electrode materials, allowing comparison of distinct aerosols within a single exposure framework. The system's modular and portable design supports straightforward switching between sources, environments, and operating parameters. Variations in aerosol properties are reflected in changes in epithelial function, cellular stress responses, and biological signalling. By integrating mobility, source diversity, and human-relevant exposure geometry, this platform provides a versatile tool for linking aerosol generation mechanisms and nanoparticle properties to biological effects.
Join Zoom Meeting
https://cesnet.zoom.us/j/95638405007
Meeting ID: 956 3840 5007
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https://cesnet.zoom.us/meetings/95638405007/invitations?signature=qbAzUKmhrnyfEnqRnCVUcyD9L08Lmg31VONzReZnTYo

