The publication of authors P. Janoš (J. E. Purkyně University in Ústí nad Labem) and P. Janoš Jr. (SISSA, Italy) with a title of Metalloenzyme-inspired approach to the design and applications of phosphatase-mimetic nanozymes. Bridging the inorganic and organic worlds was published in the prestigious journal Environmental Science - Nano.

P. Janoš and P. Janoš jr.: Metalloenzyme-inspired approach to the design and applications of phosphatase-mimetic nanozymes. Bridging the inorganic and organic worlds, Environmental Science -Nano, 11 ( 2024) 3268-3285

 https://doi.org/10.1039/D4EN00144C

Abstract: In the August issue of the Environmental Science: Nano journal, P. Janoš from UJEP together with his son (Sissa, Italy) published a fundamental critical review (perspective), in which they pointed out important analogies in the catalytic action of natural (protein-based) enzymes and so-called nanozymes. A comprehensive understanding of the interactions occurring at the interface between (predominantly inorganic) nanoparticles and complex biomolecules not only lays the foundations for new industrial branches but also holds the potential to significantly contribute to resolving fundamental questions in contemporary science, such as the origins of life on Earth. The discovery of the catalytic activity of certain metal oxides and the elucidation of the mechanisms of their action were successfully used in the recently finished international project Aquatic Pollutants and are further developed especially by the joint research teams of UJEP and UACH.