"The effect of nanoparticle exposure on DNA alterations in the human population" will be presented by Andrea Rössnerová, Ph.D. from the Institute of Experimental Medicine of AS CR on Wednesday, May 12 at 2:30 p.m. Join Zoom Meeting https://cesnet.zoom.us/j/92497051269

Background: The use of nanomaterials has been rapidly increasing during the last decade in many areas of human life. This phenomenon is accompanied by increased risk of exposure to nanoparticles (NPs). Despite many toxicological in vitro studies, the number of human in vivo studies is still limited.

In cooperation with users of NanoEnviCz infrastructure (First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague; Institute of Chemical Process Fundamentals CAS; Institute for Clinical and Experimental Medicine; Technical University in Liberec), we repeatedly (2016-2020) monitored nanocomposite research workers and matched controls. To assess the differences in exposure to particulate matter including nanosized fractions <25-100 nm, aerosol exposure monitoring during a working shift was carried out. Two cytogenetic assays and two methylation assays were used to assess the level of DNA alterations after long-term (years) and short-term (daily) exposure to NPs.

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Topic: NARECOM 5
Time: May 12, 2021 02:30 PM Amsterdam, Berlin, Rome, Stockholm, Vienna

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Meeting ID: 924 9705 1269
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